Phytochemicals, Antimicrobial, Antioxidants and Cytotoxicity Properties of the Ethanolic Extracts of Commiphora Africana and Butryospermum Paradox

The study was undertaken to evaluate the in vitro antioxidant, anti-microbial and cytotoxicity properties of methanolic extract of leaves of the plant Commiphora africana and Butryospermum paradox with a view to exploring the therapeutic potentials of the plant especially as far as treatment and management of oxidative, microbial and other related disorders are concerned. The study involved collection, identification, extraction of Commiphora africana and Butryospermum paradox leaves with ethanol. Methanolic extract of leaves of Commiphora africana and Butryospermum paradox were prepared and analyzed qualitatively for presence or absence of various phytoconstituents such as Saponins, Tannins, Flavonoid, Alkaloid, Essential oils, Glycosides, Phenols, Terpenes and Protein. Evaluation of the antioxidant and anti-microbial potentials of the plant using 2, 2'-diphenyl-1-picrylhydrazyl (DPPH), hydrogen peroxide reduction and disc diffusion method were also carried out. The plants exhibited potent and significant antioxidant and anti-microbial activities which are concentration-dependent, as well as appreciable thrombolytic activities. Moreover, the extracts compared favorably with various reference drugs used in the study. It was observed that the extract possessed bioactive components with beneficial effects in the management of oxidative, microbial and other related conditions. Presence of various phytochemical compounds in the leaves of Commiphora africana and Butryospermum paradox justifies the medicinal use of the plants. The present study results could provide future insight of this plant to be useful in pharmaceuticals for as a cure for various diseases.